Squamous Cell Carcinoma Classification

Biomedical Imaging, National Taiwan University, 2019

Optical coherence tomography (OCT) is an imaging technique that provides fast, noninvasive data collection process to reconstruct three‚Äźdimensional structures of epithelial tissue. Our full-field OCT system is able to capture images in sub-micron resolution so that all the cellular-levle information can be recorded. We integrated the FF-OCT system and a CNN-based classifier to work on the detection of squamous cell carcinoma. It achieved over 80% classification accuracy. This is made possible partly by the employment of an FF-OCT imaging system at sub-micron resolution and partly by the employment of a bottom-up feature extraction mechanism built into the classifier. This work has been published in Journal of Biophotonics.